Research Update

December 22, 2023 by

Mindfulness-Oriented Recovery Enhancement in Individuals With Opioid Use Disorder
Methadone treatment is a mainstay of therapy for opioid use disorder (OUD). However, medication treatment alone does not address the emotion dysregulation, pain, and reward processing deficits that often drive OUD. These investigators evaluated the efficacy of methadone treatment as usual (usual care) versus telehealth Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care among people with an OUD and pain.

This study was a randomized clinical trial with a total of 154 participants. Those receiving MORE plus usual care had significantly less return to drug use than those receiving usual care only. MORE plus usual care participants also had significantly lower depression scores and assessments of pain through the 16-week follow-up compared to the usual care only group.
The authors concluded that the Telehealth MORE program was a feasible adjunct to methadone treatment that had multiple positive effects including decreased drug use, pain, and depression.

Cooperman NA, Lu S, Hanley AW, et al. JAMA Psychiatry. Published online December 07, 2023.

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