Basic Research

Discovery May Help Patients Beat Deadly Pneumonia

By Josh Barney

Researchers have found that a hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients. Read more...

Michael Brown & Team Find Link Between Immune Cells, Weight Control, Disease Resistance

A research team led by UVA Nephrology‘s Michael Brown, PhD, has shown how our DNA determines our ability to fight off viruses, revealing that many genes work together to control immune cells, tissue inflammation, and even our body weight after infection. Read more...

Pediatric Nephrology Fellow Erika Rhone Receives ASPN Award

Congratulation to Erika Rhone, MD, Pediatric Nephrology Fellow and postdoctoral fellow on the UVA Nephrology T32 Training Grant, who was awarded a 2016 Trainee Research Award in Basic Science from the American Society of Pediatric Nephrology, for her project entitled “Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients. Read more...

Petri Lab’s Discovery Offers New Way to Boost Nutrition of Infants in Low-Income Countries

Caitlin Naylor, front left, and UVA alumna Lauren Hobbs, front right, were part of the research team that studied childhood malnutrition in the slums of Dhaka, Bangladesh.

UVA Today news story by Josh Barney December 15, 2015 

If every nutritional measure known to be helpful were applied to every child in the world, global malnutrition would be decreased by only a third, according to one estimate. Read more...

ID Researchers Create Immunity to E. histolytica by Manipulating Host’s Genes

Breakthrough offers new strategy to protect humans from infectious diseases:  

Study co-authors (l-r) Bill Petri, Hans Verkerke and lead author Chelsea Marie (Dan Theodorescu not pictured).

There are two common approaches to protecting humans from infectious disease: Targeting pathogens and parasites with medicines such as antibiotics, or dealing with the conditions that allow transmission. Read more...

2015 Carey-Marshall-Thorner Research & Scholars Day

With a Grand Rounds presentation by Division of Endocrinology professor Eugene Barrett on “The Changing Face of Insulin Therapy,” ten other oral presentations by Department of Medicine residents and fellows, and more than 80 poster presentations on an array of topics–including cancer mechanisms, hormones and metabolism, infections and toxins, medical education, patient safety and access, tissue injury, and vaccines and immunity–the 2015 Carey-Marshall-Thorner Research & Scholars Day on Wednesday, May 6th, presented a remarkable overview of the scholarly production of DOM trainees and faculty mentors.  Read more...

CV’s Zhen Yan Prevents Diabetic Heart Condition by Amplifying Effect of Exercise

Zhen Yan, PhD, not only researches the benefits of exercise but is an avid exerciser himself.

Zhen Yan, PhD, a professor in the Division of Cardiovascular Medicine, has magnified a benefit of exercise in mice to provide a “profound” protection from diabetic cardiomyopathy, a potentially deadly heart condition that affects many people with diabetes. Read more...

Zhen Yan, PhD

U.Va. Researchers Develop New Tool to Check Cells’ ‘Batteries’ Excerpted from UVA Today, April 7, 2014

Zhen Yan, PhDCardiologyphoto UVA Today

Under the microscope, they glow like streetlights, forming tidy rows that follow the striations of muscle tissue. Read more...

Researchers Discover New Way Human Cells Are Killed

Reprinted from a press release by Josh Barney CHARLOTTESVILLE, Va., April 9, 2014

University of Virginia School of Medicine researchers studying a potentially deadly parasitic infection have discovered an unknown ways that human cells are killed, with the parasitic amoeba essentially nibbling cells to death as a piranha might attack its prey. Read more...

The Stem Cell Transplant Team

Dr. Kindwall-Keller, Kathy DeGregory, Dr. Leonid Volodin, Dr. Laahn Foster, Hannah Spencer, Geoff Barkley

The Stem Cell Transplant team had 5 abstracts accepted at the national BMT TANDEM conference this year. Read more...