Faculty News Weekly Round-Up, June 23

June 23, 2017 by   |   Leave a Comment

UVA School of Medicine Faculty News Weekly Round-Up
June 23

Biologist Probes How Stubborn Malaria Bug Adapts to Evade Drug Treatments

About half a million people die each year from malaria, mostly children under the age of 5 who have not developed the ability to fight off the parasite that causes the disease. The danger zone is largely along Earth’s equatorial band, affecting about 3.2 billion people in large regions of Africa, South America and Asia.

“Many people in the developed world believe that the malaria problem has been largely solved, but in fact millions of people are infected and get sick each year,” said Jennifer Güler, a University of Virginia biologist who studies the malaria parasite’s ability to develop drug resistance. “It’s an ongoing problem.”

Working with researchers in UVA’s School of Medicine and the School of Engineering and Applied Science, Güler is investigating the molecular mechanisms that underlie the parasite’s ability to evolve genetic and metabolic changes that allow it to survive drug exposure. The researchers are using a range of innovative molecular, biochemical and cellular techniques, and computational modeling, to make visible, and understandable, the minute changes that occur within the parasite. This eventually could lead to a drug “cocktail” that would circumvent resistance.

Guler is Assistant Professor of Biology at the UVA School of Medicine.

Read more:

• Promotions in the Division of Infectious Diseases and International Health

Scott Heysell, MD, and Carol Gilchrist, PhD, have been promoted to Associate Professor of Medicine, in the Division of Infectious Diseases and International Health.

• UVA House Call: Dr. Matthew Barrett on Alzheimer’s Disease

Matthew Barrett, MD, Assistant Professor of Neurology, talks about UVA’s memory and aging clinic.

Watch the interview:

Did we miss something? If you have UVA School of Medicine faculty news to share, please email

Filed Under: News



Leave a Reply

Your email address will not be published. Required fields are marked *