Message from Endocrinology & Metabolism Interim Division Chief, Christopher McCartney, MD
It’s been a challenging year for our division. In addition to dealing with the psychological stress of a stubborn global pandemic, we recently experienced an unanticipated, abrupt 20-25% reduction in our capacity to provide clinical care. This required us to put a couple of specialized clinical programs on hold, and we’ve struggled (more than usual) to keep up with existing clinical demand. In some ways, it has felt as if we are simply putting our heads down and slogging ahead—doing the best we can in a very challenging situation. At the same time, I’ve been inspired by how our faculty members have continued to make academic progress and how our group has wholeheartedly engaged in several divisional projects we’ve adopted for the academic year. What I’ve appreciated the most: our faculty members have remained kind and supportive at all times.
As a division, we honor our colleagues who continue to take the brunt of the pandemic, including those in Infectious Diseases, Pulmonary/Critical Care, General and Hospital Medicine, etc. The pandemic has been hard on all of us, but we recognize that it’s been especially hard on you. We also thank Dr. Rosner and the Department of Medicine leadership for guiding and supporting us through this remarkably-challenging couple of years. May the pandemic hardships durably diminish in 2022.
I’m unapologetically using this edition of Medicine Matters as a way to honor and encourage my fellow division members. But I trust that the newsletter will contain something of interest for most everyone in the Department of Medicine. In addition to the standard Medicine Matters fare, the newsletter includes an Endocrine Division Quiz and the latest news about the ever-mysterious “Baby Endo.”
~ Christopher McCartney, MD, Interim Division Chief
Tribute to Dr. Zhenqi Liu, Division Chief 2012–2021
In July 2021, Dr. Zhenqi Liu stepped down as division chief after a long and productive tenure. Under Dr. Liu’s leadership, our division markedly expanded its clinical footprint. For example, we built an inpatient cardiovascular diabetes consult service, a transplant endocrinology service, the Advanced Diabetes Management (ADM) program, and an adult transgender care program. Dr. Liu also recruited world-class scientists such as Drs. Rita Basu, Andy Basu, and Heather Ferris, through strategic hiring initiatives, and hired outstanding early-career faculty straight out of our fellowship—Drs. Silas Culver, William (Ben) Horton, Su Hee Kim, Kaitlin Love, and Meaghan Stumpf. Our research portfolio is now more extensive than ever: in 2021, our division managed approximately 47 grants with a total combined budget of over 28 million dollars. Dr. Liu has also been a staunch supporter of our fellowship program and many other educational efforts. Our heartfelt thanks and very best wishes to Dr. Liu, who will remain busy as PI for two R01s and Co-Investigator for four R01s, all while continuing his clinical practice and mentoring future generations of clinicians and scientists!
2021 Updates on Faculty Activities
Eugene Barrett, MD, PhD, is a diabetologist, clinician-investigator, and former President of the American Diabetes Association. Dr. Barrett currently focuses his efforts on research: his areas of interest relate to insulin regulation of its own delivery to skeletal muscle; insulin promotion of its own uptake by endothelial cells; and how these actions of insulin are altered in the setting of insulin resistance, obesity, and diabetes mellitus. Dr. Barrett’s 2021 research was supported by NIH R01 HL142250 (Barrett PI – “Acute effects of hyperglycemia on the heart and skeletal muscle microvasculature”), and he served as an essential Co-Investigator for additional grants (e.g., R01 HL130296, R01 DK102359). Dr. Barrett also served as PI and Director for our NIH T32 NRSA-supported “Research Training in Neuroendocrinology & Metabolism” program. Dr. Barrett published ten peer-reviewed manuscripts in 2021 (and the first half of January 2022); he chaired a special NIH/NIDDK Review Panel for Diabetes Center (P30) applications in October 2021. He was a critical research mentor for several faculty members.
Ananda Basu, MD, is a clinician-investigator and clinical diabetologist who co-directs the Integrated Carbohydrate Physiology and Translation Laboratory. His areas of research interest include automated insulin delivery (artificial pancreas) systems, glucagon kinetics, etc. Dr. Basu’s 2021 research was funded by DP3 DK106785 (A Basu PI – “Relative Efficacy of single-, bi- and tri-hormonal closed-loop control systems”) and R01 DK085516 (A Basu PI – “Integrated Approaches to Close the Loop in Type 1 Diabetes”). He also served as an essential Co-Investigator for two R01s (DK29953 and DK124886) and an industry-sponsored trial. Dr. Basu had five peer-reviewed publications in 2021 (and the first half of January 2022), and he served on the Editorial Board for Diabetes Care and the DSMB for the RADIANT study (NIH/NIDDK). Clinically, Dr. Basu is a diabetologist who serves as Director for our Advanced Diabetes Management Clinic.
Rita Basu, MD, is a clinical researcher who co-directs the Integrated Carbohydrate Physiology and Translation Laboratory. Her areas of research interest include the pathophysiology of diabetes and insulin resistance, liver cortisol metabolism and its role in metabolic syndrome and NASH, etc. Dr. Basu’s 2021 research was funded by R01 DK29953 (R Basu PI – “Mechanisms of Insulin Resistance in Man”) and three industry-sponsored trials, and she was an essential Co-Investigator on two additional NIH grants (DP3 DK106785 and R01 DK85516). Dr. Basu had six peer-reviewed publications in 2021 (and the first half of January 2022). In 2021, Dr. Basu was appointed Chair of UVA’s IRB-Health Sciences Research. She was highlighted by the UVA Committee on Women in Medicine & Science as an outstanding institutional leader. Dr. Basu also served as the Clinical Education Director of UVA’s Center for Diabetes Technology, a member of the American Diabetes Association Scientific Session Program Planning Committee, a member of the Chronic Liver Disease Foundation Endocrinology NAFLD/NASH Steering Committee, and a member of the DSMB for the RISE Pediatric Medication Study Group.
Sue Brown, MD, is a clinical trialist whose work primarily relates to automated insulin delivery (artificial pancreas) systems. Dr. Brown’s 2021 research was supported by R01 DK085623 (Brown Co-PI – “Bio-behavioral Human Machine Co-Adaptation of the Artificial Pancreas”), R01 DK129553 (Brown Co-PI – “Advanced Artificial Pancreas Systems to Enable Fully Automated Glycemic Control in Type 1 Diabetes Mellitus”), and four industry grants. Dr. Brown published eleven peer-reviewed manuscripts in 2021, with two additional manuscripts accepted for publication in the first half of January 2022. Clinically, Dr. Brown is a general endocrinologist with a special interest in metabolic bone disease, calcium disorders, diabetes, and diabetes technology. In 2021, Dr. Brown was honored with a Patient Experience Award for the second year in a row, and she was recently listed in Best Doctors in America. Dr. Brown is a core member of our fellowship faculty, serving as one of five preceptors in our endocrinology fellows’ continuity clinic and as a member of our Clinical Competency and Program Effectiveness Committees. Fittingly, Dr. Brown was promoted to Professor of Medicine in 2021.
Robert Carey, MD, is UVA Dean Emeritus and a former President of the Endocrine Society. Dr. Carey’s 2021 research was primarily supported by NIH R01 HL128189 (Carey PI – “Renal AT2 receptors in hypertension”) and NIH P01 HL074940 (Carey PI – Project “Renal sodium-bicarbonate co-transporter (SLC4A5) activity in human subjects with salt-sensitivity of blood pressure: intrarenal mechanisms and role in blood pressure regulation”). In 2021 (and the first half of January 2022), Dr. Carey published 10 peer-reviewed manuscripts; he delivered numerous external talks; and he fulfilled numerous professional roles (e.g., Co-Chair of the Endocrine Society’s Scientific Statements Subcommittee; member of the American Heart Association’s Commission of the Hypertension Specialists and Clinicians Study Guides Planning Committee; Board of Directors for the Target:BP initiative (AMA/AHA); Senior Editor for Journal of Clinical Hypertension, Senior Advisory Editor for Hypertension, and member of Editorial Boards for Journal of Hypertension and The FASEB Journal).
Margaret Crook, MD, is a general endocrinologist with a particular interest in metabolic bone disease and calcium disorders. She co-founded Blue Ridge Endocrinology in 2010 but has practiced at UVA Endocrinology Pantops since 2015. Dr. Crook is a community referral favorite; her patient survey results are outstanding, and she was awarded a 2021 DOM Award for Excellence in Clinical Care. Our fellows highly value their rotations in her clinic. At the 2021 Recent Advances in Clinical Medicine (RACM) CME conference, Dr. Crook provided an excellent osteoporosis update.
Silas Culver, MD, is an iTHRIV scholar pursuing basic-science research related to obesity-associated kidney dysfunction and renal lipotoxicity, in addition to the role of the (pro)renin receptor in obesity-associated hypertension, aging, and cellular senescence. In 2021, Dr. Culver published two peer-reviewed manuscripts, and he delivered grand rounds at Wake Forest University. Clinically, Dr. Culver is a general endocrinologist with a particular interest in adrenal disease, endocrine hypertension, and obesity (Dr. Culver became certified by the American Board of Obesity Medicine in 2021). In addition to staffing inpatient consults and seeing outpatients at our main endocrinology clinic, Dr. Culver served the division (and Virginians) by staffing clinics in Fishersville.
Alan Dalkin, MD, is a general endocrinologist with a special interest in metabolic bone disease and calcium disorders. In addition to staffing inpatient consults and seeing outpatients at clinics in Charlottesville, Dr. Dalkin served the division (and Virginians) by staffing clinics in Fishersville. He is routinely included in Top/Best Doctors lists and in 2021 was honored with a Patient Experience Award for the third year in a row. Dr. Dalkin has been DOM Vice-Chair since 2012, and he is one of three new Associate Chief Medical Officers for Ambulatory Services. Dr. Dalkin is a core member of our fellowship faculty, serving as one of five preceptors in our endocrinology fellows’ continuity clinic and a member of our Clinical Competency and Program Effectiveness Committees. In addition, Dr. Dalkin admirably served the division in 2021 by reprising his role as System Co-Leader for Endocrinology and Reproduction (NexGen Curriculum).
Christine Eagleson, MD, is a general endocrinologist who has made exceedingly valuable contributions to the division’s clinical mission, including our regional outreach: in addition to seeing patients in our main endocrinology clinic, she served the division (and Virginians) by staffing clinics in both Culpeper and Crozet. Dr. Eagleson is also an integral part of our Transgender Health team, thus contributing to a critically-important institutional mission. Fortunately for us, Dr. Eagleson moved from a part-time to a full-time position in 2021. New responsibilities in 2021 included being a preceptor for the fellows’ continuity clinic, a change that was initiated based on fellow input. Accordingly, Dr. Eagleson became a member of our Clinical Competency and Program Effectiveness Committees.
Leon Farhy, PhD, is a biomathematician whose primary role relates to research. In 2021, Dr. Farhy’s work was supported by Center for Innovative Technology/Commonwealth Research Commercialization Fund MF20-007-LS (Farhy PI – “Machine Learning Technology for Prediction of Future Glucose Fluctuations to Enable a New Generation of Adaptive Glucose Control in Diabetes”) and UVA Strategic Investment Funding (PrIMeD) (Farhy PI – “The Biochip project”). In addition, Dr. Farhy served as an important Co-Investigator for R01 DK085516; JDRF 1-SRA-2019-818-S-B; and two industry-funded projects. Dr. Farhy also served as Associate Director of Education for UVA’s Center for Diabetes Technology.
Heather Ferris, MD, PhD, is an early-career basic scientist who was recruited from Harvard Medical School/Joslin Diabetes Center—part of the SOM Strategic Hiring Initiative—in 2017. Dr. Ferris’s areas of interest relate to brain insulin and IGF-1 action in addition to interactions among diabetes, cholesterol, and Alzheimer’s disease. Her 2021 research was supported by a large foundation grant (Ferris PI – “Discover novel binding partners of 7-ketocholesterol using clickable cholesterol probes”), NIH R03 AG070428 (Ferris PI – “The brain cholesterol interactome”), and charitable giving. Dr. Ferris received a 2021 DOM Award for Excellence in Research, and her 2021 PNAS paper generated substantial positive press. In 2021, Dr. Ferris gave presentations at the NIH’s Foundation for Advanced Education in the Sciences Endocrinology Update Review, the Vanderbilt Diabetes Research Training Center, and Virginia Commonwealth University (Endocrinology Grand Rounds). Dr. Ferris also served as a member of the American Diabetes Association’s Membership Advisory Committee and its Post-scientific Sessions Webinar Committee. Clinically, Dr. Ferris is a general endocrinologist interested in diabetes, especially in older patients.
Daniel Haisenleder, PhD, is a reproductive neuroendocrinologist with a long history of crucial basic-science research related to the regulation of gonadotropin synthesis. Dr. Haisenleder is the Director for the Ligand Assay and Analysis Core Laboratory in the Center for Research in Reproduction, a busy research laboratory supported by NIH R24 HD102061. This role includes the development and refinement of hormone assays. For example, Dr. Haisenleder recently developed an ultra-sensitive LH assay for rodents, and this has become an essential tool for numerous reproductive neuroendocrinology investigators across the country. Dr. Haisenleder continues to serve as a member of the University of Virginia Animal Care and Use Committee and an External Advisory Board Member for the Wisconsin National Primate Center.
Gregory Hong, MD, PhD, is a general endocrinologist with a particular interest in neuroendocrinology and pituitary disease: he is an integral part of our multidisciplinary pituitary program. In addition to being a highly-skilled clinician, Dr. Hong is an outstanding educator and has continued to do an exceptional job as our fellowship program director. Dr. Hong serves as one of five preceptors in our endocrinology fellows’ continuity clinic and Chairs our Clinical Competency and Program Effectiveness Committees. In 2021, he was Co-Chair of the Association of Program Directors in Endocrinology, Diabetes, and Metabolism’s (APDEM’s) Fellowship Recruitment Subcommittee/COVID-19 Task Force; and he was a question writer and reviewer for the American Association of Clinical Endocrinology’s Self-Assessment Program.
William (Ben) Horton, MD, is an iTHRIV scholar pursuing clinical research to investigate the effects of acute hyperglycemia on skeletal and cardiac muscle microvasculature. In 2021, Dr. Horton received research support from a UVA Launchpad for Diabetes grant; he functioned as a Co-Investigator on NIH R01 HL142250, and he published eight peer-reviewed manuscripts. Also, in 2021, Dr. Horton was a member of the American Association of Clinical Endocrinology’s Diabetes Disease State Network; he was part of the 15-member ACGME Endocrinology, Diabetes, and Metabolism Milestones Work Group that revised fellowship milestones (implemented in 2021); and he delivered grand rounds endocrinology at Wake Forest University. Clinically, Dr. Horton is a general endocrinologist with a particular interest in diabetes. In addition to staffing inpatient consults, Dr. Horton served the division (and Virginians) by staffing clinics in Zions Crossroads.
Susanna Keller, MD, is a basic research scientist whose areas of research interest include insulin signaling, regulation of metabolism/energy homeostasis, insulin-regulated membrane trafficking, and nutrigenomics. In 2021, Dr. Keller was a Co-PI on a UVA Engineering in Medicine Seed Award (“Nutrigenomics for Precision Health”), and she was an essential Co-Investigator on a number of grants (NIH R01 HL135018; American Diabetes Association 1-19-IBS-105 Research Award; NIH R01 DK118287; NIH R01 HL128189; NIH R01 HL155165; NIH R01 AI140405; NIH R01 HL123627; NIH R01 HL128189; NIH R01 DK114875). Dr. Keller had three peer-reviewed manuscripts in 2021. Dr. Keller continued to serve as a member of the UVA Animal Care and Use Committee, and she was a valuable contributor to several SOM educational efforts.
Su Hee Kim, MD, is a clinical researcher supported by a K23 career-development grant (2019–2024) entitled “Pathophysiology and therapeutic strategy for late reproductive-aged women with PCOS.” She is currently pursuing studies to explore the comparative pathophysiology of hyperandrogenism in older vs. young women with polycystic ovary syndrome (PCOS) and to define the relative desirability of metformin vs. combined oral contraceptive pills for the treatment of PCOS in women of later reproductive age. Dr. Kim is also pursuing a Master of Clinical Research (Public Health Sciences). In 2021, Dr. Kim delivered Grand Rounds presentations at Wake Forest University and VCU. Clinically, Dr. Kim is a general endocrinologist specializing in polycystic ovary syndrome, and she is certified by the American Board of Obesity Medicine. In addition to staffing inpatient consults and seeing outpatients at clinics in Charlottesville, Dr. Kim served the division (and Virginians) by staffing clinics in Fishersville.
Jennifer Kirby, MD, PhD, is a general endocrinologist specializing in diabetes and obesity (she is certified by the American Board of Obesity Medicine). In addition to staffing inpatient consults and seeing outpatients at our main endocrinology clinic, Dr. Kirby served the division (and Virginians) by staffing clinics in Fishersville. In 2021 she was honored with a Patient Experience Award for the third year in a row, and she was recently listed in Best Doctors in America. Dr. Kirby is our division’s Associate Chief for Clinical Affairs, the Medical Lead for our Endocrinology and Metabolism clinic (this requires a tremendous amount of work!), Director of our Cardiovascular Diabetes Consult Service and Co-Medical Lead for Inpatient Glycemic Management. In addition to being a highly-skilled clinician, she is an outstanding educator and mentor.
Susan Kirk, MD, is a general endocrinologist with a particular interest in endocrine disorders in pregnancy and transgender medicine, and she is consistently included in Top/Best Doctors lists. Dr. Kirk continues to do remarkable work on behalf of marginalized groups (e.g., she has been a strong and effective advocate for gender-diverse patients at UVA). She is an integral part of our Transgender Health team. Dr. Kirk has been our Designated Institutional Official and Associate Dean for Graduate Medical Education since 2006. She is a national GME leader (e.g., she was Chair of the ACGME’s Institutional Review Committee from 2017 to 2020), and she received a 2021 DOM Award for Excellence in Teaching. Dr. Kirk is currently the 2021–2022 Chair of the University of Virginia Faculty Senate. She was recently highlighted by the UVA Committee on Women in Medicine & Science as an outstanding institutional leader.
Zhenqi Liu, MD, is a clinician-investigator whose primary interests relate to regulating insulin action in the vasculature and the cardiovascular complications of diabetes. Dr. Liu’s 2021 research was supported by R01 DK125330 (PI Liu – “Effects of Exercise and GLP-1R Agonism on Muscle Microvascular Perfusion and Insulin Action”) and R01 DK124344 (Co-PI Liu – “Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness in Diabetes”). Dr. Liu served as an essential Co-Investigator for four additional R01s (HL142250, HL130296, DK116768, HL129510). In 2021, Dr. Liu published at least six peer-reviewed manuscripts; he served on the Endocrine Society’s Publications Core Committee and Global Engagement Advisory Group; and he became an Associate Editor for the Journal of the Endocrine Society. Clinically, Dr. Liu is a general endocrinologist interested in diabetes and thyroid disease, and he is routinely included in the America’s Top/Best Doctors lists.
Kaitlin Love, MD, is an iTHRIV scholar pursuing clinical research related to micro-and macrovascular insulin resistance in type 1 diabetes and response to GLP-1-receptor agonism and exercise treatment. She is also an essential Co-Investigator for NIH R01 DK124344. In 2021, Dr. Love published five peer-reviewed manuscripts, and she delivered Grand Rounds endocrinology at Wake Forest University. Clinically, Dr. Love is a general endocrinologist with a particular interest in diabetes.
Ralf Nass, MD, is a general endocrinologist who has made valuable contributions to the division’s clinical mission, including our regional outreach. In addition to seeing patients in our main endocrinology clinic, he served the division (and Virginians) by staffing clinics in Culpeper. He also contributed significantly to our Cardiovascular Diabetes Consult Service consult efforts. Dr. Nass has been an exceptional divisional citizen, routinely volunteering to cover in the setting of unanticipated faculty absences. Dr. Nass has also engaged with research in partnership with the Center for Diabetes Technology, and in 2021 he wrote a chapter for Yen and Jaffe’s Reproductive Endocrinology—widely considered to be the premier reproductive endocrinology textbook.
Helmy Siragy, MD, is a clinician-scientist whose primary interests relate to the endocrine/paracrine control of blood pressure and renal function. His 2021 research was supported by NIH R01 HL091535 (Siragy PI – “Prorenin Receptor Mediates Early Changes in Diabetic Kidney”) and NIH R01 DK114875 (Siragy PI – “(Pro)renin receptor mediates obesity-induced hypertension”). In 2021, Dr. Siragy published three peer-reviewed manuscripts, served as the Division’s Associate Chief for Research, and adeptly organized the division’s Research in Progress conference. Dr. Siragy also fulfilled numerous professional roles (e.g., standing member of NIH Pathobiology of Kidney Disease Study Section; Editorial Boards for Integrated Blood Pressure Control and Nature Research Group [Scientific Reports/Medicine/Endocrinology]). Clinically, Dr. Siragy is a general endocrinologist with a particular interest in adrenal disease and endocrine hypertension; in addition to staffing inpatient consults, he served the division (and Virginians) by staffing clinics in Zions Crossroads.
Meaghan Stumpf, MD, is a general endocrinologist interested in diabetes and transplant endocrinology. Indeed, Dr. Stumpf initiated (and continues to develop) our division’s transplant endocrinology program, which involves strong partnerships with the solid abdominal transplant group. Dr. Stumpf received a 2021 DOM Award for Excellence in Clinical Care, and in 2021 she was honored with a Patient Experience Award for the second year in a row. Dr. Stumpf also engaged in research with the Center for Diabetes Technology—related to continuous glucose monitoring in patients receiving intermittent dialysis—and in 2021, she wrote a chapter for the second edition of the textbook Pancreas Transplantation.
Mary Lee Vance, MD, is a medical neuroendocrinologist who forms the backbone of our multidisciplinary pituitary program. She is a world-renowned expert in pituitary disease, and she is routinely included in the America’s Top/Best Doctors lists. Dr. Vance is a former President of the Pituitary Society, and in 2019 received a Pituitary Society Lifetime Achievement Award. Although most of Dr. Vance’s efforts are dedicated to patient care, she continues to contribute to substantive team-based research efforts and education.
• Michele Hamrick RN, ANP, MSN, is an outpatient endocrine nurse practitioner who cares for a substantial number of our endocrine patients. Cherie Chaney RN, MSN, FNP, and Elaine Hannah RN, MSN, AG-ACNP, are nurse practitioners who staff the division’s Cardiovascular Diabetes Consult Service. These individuals play critically-important roles in our clinical care mission.
• Our Emeritus Professors include Drs. William (Bill) Evans, MD; John Marshall, MD, PhD; Anthony (Tony) McCall, MD, PhD; Richard Santen, MD; Margaret (Peggy) Shupnik, PhD; and Michael Thorner, MBBS. We understand that all have enjoyed a much-deserved respite from their long and highly-productive work careers, and some remain very active in our division’s activities. For example, Dr. Richard Santen continues to see patients and provide remote diabetes care to underserved patients via federally-funded Community Health Centers in southwestern Virginia.
A Fond Farewell to Esteemed Colleagues
A handful of our faculty members left the University in 2021. Dr. Jessica Lundgren joined our faculty in 2018 after graduating from our fellowship program. In addition to practicing general endocrinology, she made valuable contributions to multidisciplinary efforts related to transgender care and thyroid cancer. Dr. Lundgren currently cares for endocrine patients via telemedicine through Penn Highlands Endocrinology.
Dr. Shetal Padia joined our faculty in 2007 after graduating from our fellowship program. Dr. Padia developed substantial clinical expertise in endocrine hypertension and adrenal disease as a faculty member. She was NIH-funded (K08 and subsequent R01) to study the role of the intrarenal ghrelin system and its role in obesity-induced hypertension. Moreover, from 2015 to 2021, she was the System Co-Leader for the Endocrinology and Reproduction section of the School of Medicine’s NexGen Curriculum. Dr. Padia moved to Pennsylvania in 2021 for family-related reasons.
Mary Voelmle is a Family Nurse Practitioner and Certified Diabetes Care and Education Specialist who played significant roles in the Advanced Diabetes Management Clinic and Center for Diabetes Technology from 2018 to 2021; she is now a Medical Science Liaison at LifeScan.
We remain very fond of these talented former colleagues, and we wish each of them the very best.
In Memoriam: Drs. Stacey Anderson and Bruce Gaylinn
The division is heartbroken to have lost two of its own in the latter half of 2021. Despite the protracted and debilitating nature of their illnesses, they both remained steadfastly generous, outward-focused, and kindhearted. We remember them with great fondness, and we aim to honor them in our work and by the way we continue to support each other.
Dr. Stacey Anderson received a BS in Molecular Biology and medical degree from Vanderbilt University. She came to UVA for both IM Residency and Endocrinology/Metabolism Fellowship. Her initial research interest related to estrogen neuromodulation of the growth hormone axis, but her interests eventually shifted towards diabetes. Dr. Anderson was appointed Medical Director of the Center for Diabetes Technology, and she became an internationally-recognized expert in automated (closed-loop) insulin-delivery systems (i.e., artificial pancreas technology). Dr. Anderson was recognized as an outstanding physician with special interests in diabetes and thyroid disease. Dr. Anderson was promoted to full Professor in 2021, shortly before her untimely death. Dr. Anderson is survived by family members Henry Carrington Lancaster III (husband); Rachel Ann Gildersleeve, Henry Carrington Lancaster IV, Max Arthur Lancaster, and Thomas Alexander Lancaster (children); Gordon Paul and Darlene Anderson (parents); Nicole Siira (sister); and Anthony Anderson (brother). Dr. Anderson’s obituary may be found here.
Dr. Bruce Gaylinn obtained a BS in Biology and a PhD in Biophysics from Rensselaer Polytechnic Institute (Troy, NY). He pursued muscle physiology research at SUNY Stony Brook and then at the University of Virginia. Dr. Gaylinn joined the endocrinology division in 1992 to study growth and hunger, and he had exceptionally-productive collaborations with, among others, division members Drs. Michael Thorner, Ralf Nass, and Leon Farhy. Dr. Gaylinn is survived by family members Sandie Gaylinn (wife), Nathan Gaylinn (son), and Renee Ritter (sister). Dr. Gaylinn’s obituary may be found here.
Well Wishes for a Happy Retirement – Dr. Peggy Shupnik
Dr. Margaret (Peggy) A. Shupnik, Gerald D. Aurbach Professor in Endocrinology, retired in March 2021 after an absolutely tremendous career.
Dr. Shupnik obtained her Bachelor of Science degree at Pennsylvania State University and PhD at the University of Wisconsin, after which she was a Postdoctoral NIH Research Fellow at the Harvard School of Public Health. After six years on faculty at Harvard Medical School, Dr. Shupnik came to the University of Virginia (1988) as an Associate Professor of Medicine and Physiology. Dr. Shupnik was awarded tenure in 1992, was promoted to Professor of Medicine and Physiology in 1995, and became the Gerald D. Aurbach Professor in Endocrinology in 2011.
Her exceptional research career contributed substantively to our understanding of thyroid hormone action, reproduction (e.g., mechanisms by which GnRH pulse frequency differentially controls gonadotropin gene transcription), and steroid-responsive cancers (e.g., mechanisms by which estrogens and antiestrogens impact breast cancer). Dr. Shupnik published 126 peer-reviewed publications, with 7331 total citations and an h-index of 50. While at UVA, Dr. Shupnik’s research support included, but was certainly not limited to: NIH R01 HD25719 (1989–1999); NIH R01 DK57082 (1989–2008); R44 DK44142 Shannon Award (1991–1993); R01 DK44142 (1992–1997); and several R01 equivalents as part of NIH U54 HD28934 (1998–2015). Dr. Shupnik was also PI and Director for NIH T32 NRSA “Research Training in Neuroendocrinology” (1995–2015) and was the Women’s Oncology Program Leader for the University of Virginia’s NIH P30 Cancer Center Grant (2012–2017).
Dr. Shupnik received a 1995 University of Virginia Dean’s Award for Teaching Excellence, and in 2003 she became a Charter Member of the Academy of Distinguished Educators (now called Academy for Excellence in Education). Dr. Shupnik has been a formal mentor to many notable endocrine clinicians and scientists, including Drs. Douglas Ross, Susan Greenspan, Randall Urban, Laurel Rice, and Heather Ferris. (Dr. Shupnik was also an important role model and sponsor for the author of this tribute.)
Dr. Shupnik’s accolades are legion. Selected awards include the 1992 American Thyroid Association Van Meter Award for Research, the 1993 Endocrine Society Ernst Oppenheimer Award for Research, the 1994 Pituitary Society Young Investigator Award, and the 2004 Endocrine Society Sidney H. Ingbar Award for Distinguished Service. Dr. Shupnik was a member of several editorial boards and was an Associate Editor for the International Journal of Endocrinology. She also served on numerous review panels, including as Chair (e.g., Chair of NIH Biochemical Endocrinology Study Section; Chair of NIH Special Emphasis Panel,
Fellowship Review ZRG1, F06E, Diabetes, Nutrition, Obesity, Reproduction Sciences; Chair of the NIH Distinguished Editorial Panel for the review of applications for Centers of Research on Sex Differences [P50]).
She was a member of numerous committees with the American Thyroid Association, the Society for the Study of Reproduction, FASEB, Women in Endocrinology, and the Endocrine Society. Dr. Shupnik’s leadership positions in the Endocrine Society—arguably the world’s most prestigious professional organization for endocrinology—included: Council/Board of Directors (1995–1998), Secretary-Treasurer (1998–2004), Chair of Strategic Planning Committee (2001–2002), Chair of Research Affairs Committee (2004–2006), Chair of Publications Committee (2009–2015), and President (2006–2008). Dr. Shupnik also served on the International Society of Endocrinology (ISE) Executive Committee (2010–2016), including as its Chair (i.e., ISE President) (2012–2016).
Here at home, Dr. Shupnik was the University of Virginia School of Medicine’s Associate Dean for Basic Research (2004–2010), Senior Associate Dean for Research (2010–2021), and Associate Vice President for Research–Medical Sciences (2015–2019). And Dr. Shupnik’s contributions to the University in these roles were truly exceptional. For example, Dr. Shupnik established K programs leading to an 80% increase in successful K and K-to-R transitions. She developed/organized School of Medicine Bridge, GAP, and Pilot Funding programs. She organized and developed pan-University efforts on research in the neurosciences, leading to the UVA-BRAIN project. She substantively contributed to the University of Virginia’s successful CTSA application (awarded in 2019). She developed the first clinical/translational research building for the University of Virginia (the Ivy Building), the first cGMP cellular therapy facility for clinical research in Virginia, and the first inducible pluripotent adult stem cell (iPSC) core in the state. She developed new Clinical Research Units and cores. She developed a network of shared research facilities among Virginia state universities. She directed Hartwell scholar and investigator awards and established the Pinn Scholar Program for mid-career scientists. She was Co-Chair of the School of Medicine’s Strategic Hiring Committee, which hired 25 established physician-scientists and translational scientists, increasing the School’s research funding by 33% over two years. (The list goes on.)
The division, Department of Medicine, School of Medicine, and University owe Dr. Shupnik a tremendous debt of gratitude, and we wish her the very best for a long and fulfilling retirement!
Well Wishes for a Happy Retirement – Dr. John Marshall
Dr. John C. Marshall, MD, PhD, Andrew D. Hart Professor of Medicine of Endocrinology, retired in January 2022 after a long and extraordinarily successful career.
Shortly after completing his training in the United Kingdom, Dr. Marshall was recruited to the University of Michigan, where he quickly achieved promotion to Professor and served as the Department of Internal Medicine’s Director of House Officer Programs and Associate Chairman for Graduate Education (1983–1986); Associate Chairman for Research Programs (1986–1987); Chief of Division of Endocrinology and Metabolism (1987–1990); and Interim Chairman, Department of Internal Medicine (1989–1990).
Dr. Marshall was recruited to the University of Virginia by Dean Robert Carey in 1991, and he served as the Department of Medicine Chair and Physician in Chief of University of Virginia Hospitals from 1991 to 1996.
Dr. Marshall demonstrated profound excellence in research, clinical care, education, and mentorship throughout his career.
Dr. Marshall is a world-renowned expert in reproductive neuroendocrinology, and he was Director for the University of Virginia’s Center for Research in Reproduction—which he founded—since 1996. Since coming to the University of Virginia, Dr. Marshall was PI on at least ten R01 or equivalent grants; was overall PI on five NIH center grants (funded by P30, U54, and P50 mechanisms); and was PI/Director for three cycles of a reproduction-focused T32 NRSA training grant. Dr. Marshall has published at least 188 peer-reviewed publications, received at least 15,183 citations, and has an h-index of 69.
Dr. Marshall has also been an essential mentor to numerous DOM and SOM faculty members, including Drs. Susan Kirk (Assoc. Dean for GME and DIO) and Alan Dalkin (DOM Vice-Chair; ACMO for Ambulatory Services). (He was also the primary research mentor and an important role model for the author of this tribute.) Clinically, Dr. Marshall was an integral member of UVA’s highly-regarded multidisciplinary pituitary program. He also practiced as a general endocrinologist (specializing in medical reproductive endocrinology) and a general internist (inpatient wards).
Dr. Marshall has been nationally and internationally recognized for his achievements and service, bringing great honor to the University. For example, Dr. Marshall received the 2008 Clinical Investigator Award and the 2020 Outstanding Leadership Award from the Endocrine Society—arguably the world’s most prestigious professional organization in endocrinology.
Dr. Marshall also served as Endocrine Society’s Secretary-Treasurer (2010–2013) and held numerous other leadership positions with the Society: Committee on Scientific Programs (1987–1989), Nominating Committee (1990–1992), Recent Progress in Hormone Research Program Committee (1993–1998), representative to the International Society of Endocrinology (1996–2000), Finance Committee (1996–2000, 2005–2008, Chair 2011–2013), Investment Subcommittee (2005–2013, Chair 2010–2013), Operations Committee (Chair 1997–1998), Council/Board of Directors (2000–2003), Publications Core Committee (2010–2013), Executive Committee (2010–2013), and Nominating Committee (2013–2016). Dr. Marshall also served as Editor for Endocrinology, the Endocrine Society’s flagship basic science journal (1979–1983).
Additional national leadership positions of interest included: the American Board of Internal Medicine (ABIM) Endocrinology and Metabolism Subspecialty Committee (1983–1989); the ABIM Certifying Examination Pretest Committee (1991–1992); the American College of Physicians (ACP) Endocrinology and Metabolism Subspecialty Committee, MKSAP IX (1989–1991); the ACP In-Training Examination Committee (1995–1998); and the ACP Annual Session Scientific Program Subcommittee (2001–2002).
Additional honors of interest included: election as a Fellow of the Royal College of Physicians of London (1980); election as a Fellow of the American College of Physicians (1980); induction into the American Society for Clinical Investigation (1981); and induction as an honorary member of AOA (1984). Dr. Marshall was an editor for DeGroot’s Endocrinology, a premiere endocrinology text, from 1988 to 2010; and he provided tremendous service to the NIH (e.g., Board of Scientific Counselors [1983–1987]; numerous study sections/review panels, including as Chair; external reviewer/counselor for the Developmental Endocrinology Branch, the Clinical Research Branch, and the Endocrinology and Reproduction Research Branch; Chair of the review panel for the National Cooperative Program for Infertility Research; Specialized Cooperative Centers Program in Reproduction Research Steering Committee; and panelist for the NIH Evidence-based Methodology Workshop on PCOS).
We thank Dr. Marshall for the way he unreservedly invested himself in others and for his undying enthusiasm for science and endocrinology. We wish Dr. Marshall the very best for a long and fulfilling retirement!
2021 Fellowship Updates
2021 Fellowship Match:
We’re exceedingly excited about our 2021 Match!
Dr. Katherine Mustafa attended medical school at DeBusk College of Osteopathic Medicine and is completing her IM residency at Virginia Tech Carilion.
Dr. Lisette Rodriguez attended medical school at Instituo Techologico de Santo Domingo and is completing her IM residency at Florida State University.
Dr. Angela Vuong attended medical school at East Carolina University and is completing her IM residency at Wake Forest University.
Also of note: Once again, Dr. Gregory Hong and Ms. Javanov Barksdale expertly met the challenge of recruiting during a pandemic. For the 2021 recruitment season, Dr. Hong organized what we think is an exceptional recruitment video which you may enjoy below.
Other Divisional Updates
• Our division recently hired two new NPs to join Cherie Chaney and Elaine Hannah on the Inpatient Diabetes Consult Service: Milford George, MSN, FNP (MSN at Winston-Salem State University 2019) and Caleb Helsley, MSN, FNP (MSN at Old Dominion University 2020). Many thanks to the search committee who recruited these outstanding NPs: Cherie Chaney, MSN, FNP; Elaine Hannah, MSN, AG-ACNP; Jennifer Kirby, MD, PhD (Chair); Christopher McCartney, MD, Meaghan Stumpf, MD.
• Jessica Proffitt has joined the division as Operations Manager starting Jan 1, 2022. She has been at UVA for 11.5 years, most recently as Operations Manager for General/Geriatric/Palliative/Hospital Medicine. Welcome Jessica!
• Charlotte Odom has joined the division as administrative support for Drs. Rita and Andy Basu. She was previously the Executive Assistant for UVA SOM COO, and the Sr. Admin. Asst. to Sr. Assoc. Dean of Research (Dr. Shupnik). Welcome Charlotte!
• The Virginia Center Diabetes Prevention & Education has hired two new members: Lorrie Rilko, DNP, ADM, as Education and Outreach Manager, and Jaelyn Munson, as Senior Administrative Coordinator and Health Educator. We offer a warm welcome to both!
• Our division is actively seeking to recruit two new Clinical Faculty members. Many thanks to the search committee for leading the charge: Ananda Basu MD; Sue Brown, MD; Margaret Crook, MD; Su Hee Kim, MD; and Christopher McCartney, MD.
• Drs. Stacey Anderson and Sue Brown were promoted to Professor of Medicine in 2021.
• Dr. Rita Basu was appointed Chair of the UVA IRB for Health Sciences Research (IRB-HSR) in July 2021.
• Dr. Susan Kirk serves as the 2021–2022 Chair of the Faculty Senate.
• Dr. Susan Kirk is serving as Co-Chair for UVA Health’s Strategic Planning Work Group for Education.
• A number of our faculty members—Drs. Sue Brown, Alan Dalkin, Jennifer Kirby, and Meaghan Stumpf—received 2021 Patient Experience Awards, indicating patient satisfaction scores in the top 5%.
• Drs. Margaret Crook and Meaghan Stumpf received 2021 DOM Awards for Excellence in Clinical Care; Dr. Heather Ferris received a 2021 DOM Award for Excellence in Research, and Dr. Susan Kirk received a 2021 DOM Award for Excellence in Teaching.
• Our division now has three faculty members certified by the American Board of Obesity Medicine: Drs. Jennifer Kirby (since 2017), Su Hee Kim (since 2020), and Silas Culver (since 2021).
• A number of our faculty members served on scientific journal editorial boards in 2021, including Drs. Eugene Barrett (American Journal of Physiology-Endocrinology & Metabolism; Journal of Clinical Endocrinology and Metabolism), Rita Basu (American Journal of Physiology-Endocrinology & Metabolism; Diabetes Care), Ananda Basu (Diabetes Care), Robert Carey (Journal of Hypertension; The FASEB Journal); Zhenqi Liu (Journal of Central South University (Medical Sciences); Chinese Journal of Diabetes; World Journal of Diabetes), Christopher McCartney (Journal of Clinical Endocrinology and Metabolism), and Helmy Siragy (Integrated Blood Pressure Control; Nature Research Group [Scientific Reports/Medicine/Endocrinology]). Dr. Robert Carey served as a Senior Editor for Journal of Clinical Hypertension and a Senior Advisory Editor for Hypertension; Dr. Jennifer Kirby served as a Review Editor for Frontiers in Diabetes. Dr. Zhenqi Liu became an Associate Editor for the Journal of the Endocrine Society.
• A number of our faculty members served on NIH study sections in 2021, including Drs. Eugene Barrett (Chair of Special NIDDK Review Panel for Diabetes Center [P30] applications), Rita Basu (Small Business Special Emphasis Panel, Digestive, Kidney and Urological Systems Integrated Review Group), Leon Farhy (NIDDK Diabetes, Endocrinology, and Metabolic Diseases B Study Section), Susanna Keller (standing member of NIDDK Special Emphasis Panel for R13 applications), Christopher McCartney (standing member of NICHD Reproduction, Andrology, and Gynecology Study Section), and Helmy Siragy (standing member of Pathobiology of Kidney Disease Study Section). Dr. Zhenqi Liu was a reviewer for the Research Grants Council of Hong Kong and the Department of Defense Medical Research Program.
• Expertscape recently recognized Dr. Richard Santen as a world expert in the field of menopause. In particular, Expertscape determined that Dr. Santen ranked in the top 0.1% of scholars writing about menopause over the past ten years.
• A number of our faculty members served on professional organization committees in 2021, including Drs. Rita Basu (American Diabetes Association Scientific Session Program Planning Committee; Chronic Liver Disease Foundation Endocrinology NAFLD/NASH Steering Committee), Robert Carey (Co-Chair of the Endocrine Society’s Scientific Statements Subcommittee; Chair of the Endocrine Society’s Baxter Medal Selection Committee; member of the American Heart Association’s Commission of the Hypertension Specialists and Clinicians Study Guides Planning Committee; Search Committee Chair for the Editor-in-Chief of Hypertension; Board of Directors for the Target: BP initiative [American Medical Association/American Heart Association]), Gregory Hong (Co-Chair of the Association of Program Directors in Endocrinology, Diabetes, and Metabolism’s Fellowship Recruitment Subcommittee/COVID-19 Task Force; question writer/reviewer [pituitary section] for the American Association of Clinical Endocrinology’s Self-Assessment Program), William (Ben) Horton (American Association of Clinical Endocrinology’s Diabetes Disease State Network), Zhenqi Liu (Endocrine Society’s Publications Core Committee; Endocrine Society’s Global Engagement Advisory Group), Christopher McCartney (Chair of the Endocrine Society’s Conflict of Interest Advisory Group; question writer/reviewer [reproduction section] for the American Association of Clinical Endocrinology’s Self-Assessment Program), and Meaghan Stumpf (Early Career Representative on the American Diabetes Association’s Immunology, Immunogenetics, and Transplantation Interest Group Leadership Team). In 2021, Dr. Christopher McCartney was selected to be the Clinical Science Chair for the Endocrine Society’s 2023 Annual Meeting.
• Dr. Rita Basu is currently a member of the development panel for the American Association of Clinical Endocrinology’s clinical practice guideline regarding NASH/NAFLD, and Dr. Christopher McCartney is presently a methodologist member of the development panel for the Endocrine Society’s clinical practice guideline related to vitamin D deficiency.
• Dr. Heather Ferris, our new Endocrine Grand Rounds (EGR) Course Director, has assembled a truly remarkable speaker lineup for the 2021–2022 academic year, including the following external speakers: Susan Samson, MD, PhD (Mayo Clinic Jacksonville) [special joint Endocrine Grand Rounds with VCU]; Ritu Madan, MD (VCU); Rita Kalyani, MD (Johns Hopkins); Mary Elizabeth Patti, MD (Joslin/Harvard); Kristy Brown, PhD (Weill Cornell); Matthew Gorris, MD (Wake Forest); Theresa Hillier, MD (Kaiser Permanente Center for Health Research) [Thorner Lectureship]; Jacqueline Jonklaas, MD, PhD (Georgetown) [Dunn Lectureship]; Gary Hammer, MD, PhD (Michigan) [Crispell Lectureship]; Andrea Dunaif, MD (Mount Sinai) [sponsored by Center for Research in Reproduction].