{"id":3130,"date":"2021-10-03T18:04:40","date_gmt":"2021-10-03T22:04:40","guid":{"rendered":"https:\/\/news.med.virginia.edu\/kidsmatter\/?p=3130"},"modified":"2021-10-03T18:04:40","modified_gmt":"2021-10-03T22:04:40","slug":"covid-19-childrens-corner-october","status":"publish","type":"post","link":"https:\/\/news.med.virginia.edu\/kidsmatter\/covid-19-childrens-corner-october\/","title":{"rendered":"COVID-19 Children\u2019s Corner: October"},"content":{"rendered":"<p><strong><em>COVID-19 children\u2019s corner: brief updates on epidemiology, variants, vaccines and more\u2026<\/em><\/strong><\/p>\n<p><em>by Dr. Debbie-Ann Shirley, MD<\/em><\/p>\n<p><strong><em>The pandemic and children<\/em><\/strong><strong>.<\/strong>\u00a0Nearly\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=Wh2JmMI3-Cudj_57EKrK_FX04zx1Zbo4VjZwIvwNX-HM-weJNYXZCAFodHRwczovL3NlcnZpY2VzLmFhcC5vcmcvZW4vcGFnZXMvMjAxOS1ub3ZlbC1jb3JvbmF2aXJ1cy1jb3ZpZC0xOS1pbmZlY3Rpb25zL2NoaWxkcmVuLWFuZC1jb3ZpZC0xOS1zdGF0ZS1sZXZlbC1kYXRhLXJlcG9ydC8.\">5.8 million<\/a>\u00a0child cases of COVID-19 have been reported in the United States to date, with at least 561 deaths. Nationally over 206,864 new child COVID-19 cases were reported\u00a0in the week ending September 23<sup>rd<\/sup>, with children accounting for 26.7% of weekly COVID-19 cases. Children are still less likely to be hospitalized or die from COVID-19 when compared to adults, but severe outcomes in children can occur. Locally, we witnessed a sharp rise in pediatric COVID-19 associated hospitalization, mirroring the national trends among children and adolescents since the rise of the delta variant. Hospitalizations among unvaccinated adolescents are\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=FTV9yT3EI0Y521LjGCM7uu2ETT7AC4Cmk0gfdJFGhkjM-weJNYXZCAFodHRwczovL3d3dy5jZGMuZ292L21td3Ivdm9sdW1lcy83MC93ci9tbTcwMzZlMi5odG0.\">ten times higher<\/a>\u00a0than in those fully vaccinated. We have also seen a rise in new MIS-C cases over the past month,\u00a0keeping in trend with expected lag time behind COVID-19 cases. To date over\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=oz-C3pggAtfMYXNdoHFhePXKLD6VH8ErFFY8_rSfkevM-weJNYXZCAFodHRwczovL2NvdmlkLmNkYy5nb3YvY292aWQtZGF0YS10cmFja2VyLyNtaXMtbmF0aW9uYWwtc3VydmVpbGxhbmNl\">4,661<\/a>\u00a0patients have been diagnosed with the severe multisystem inflammatory syndrome in children following COVID-19 infection in the US, including 85 children from\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=E9u657Lmaa9yopsfclI6c4VuYiJdMG9jY6NvPQ_IJzbM-weJNYXZCAFodHRwczovL3d3dy52ZGgudmlyZ2luaWEuZ292L2Nvcm9uYXZpcnVzL2NvdmlkLTE5LWluLXZpcmdpbmlhLW1pcy1jLw..\">Virginia<\/a>, of which nearly 20 were treated in our Children\u2019s Hospital. MIS-C remains a reportable condition.<\/p>\n<p><strong><em>Variants of concern.<\/em><\/strong>\u00a0The delta (B.1.617) variant, which quickly emerged to become the predominant variant in the US, continues to account for almost all cases that we see locally and nationally representing &gt;<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=WF-4ZFwSPPK_X_p2VyOpwU8hwTcnuUIsD-wqlMYJ_cPM-weJNYXZCAFodHRwczovL2NvdmlkLmNkYy5nb3YvY292aWQtZGF0YS10cmFja2VyLyN2YXJpYW50LXByb3BvcnRpb25z\">99% of viral lineages<\/a>.\u00a0Vaccines remain effective at preventing severe disease, even from the delta variant, so we should continue to strive to\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=2GhqJ9KC6oj58eWhV-xf_-2x12y4JxBWJIaDR1sLVxjM-weJNYXZCAFodHRwczovL2VtZXJnZW5jeS5jZGMuZ292L2hhbi8yMDIxL2hhbjAwNDQ3LmFzcA..\">increase vaccination coverage<\/a>\u00a0for those who are eligible to receive a primary series. Following an FDA EUA\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=IWsi4lmRoomZKo3j2_ySmXdjw6d-3sQFKLYBtfXBR0HM-weJNYXZCAFodHRwczovL3d3dy5mZGEuZ292L25ld3MtZXZlbnRzL3ByZXNzLWFubm91bmNlbWVudHMvZmRhLWF1dGhvcml6ZXMtYm9vc3Rlci1kb3NlLXBmaXplci1iaW9udGVjaC1jb3ZpZC0xOS12YWNjaW5lLWNlcnRhaW4tcG9wdWxhdGlvbnM.\">amendment<\/a>, on September 23<sup>rd<\/sup>\u00a0the CDC now recommends\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=Bxx7rQAKmE6jpGU6oZ16GaTVU6rUCc09OcTx8q9JOGrM-weJNYXZCAFodHRwczovL3d3dy5jZGMuZ292L3ZhY2NpbmVzL2NvdmlkLTE5L2NsaW5pY2FsLWNvbnNpZGVyYXRpb25zL2NvdmlkLTE5LXZhY2NpbmVzLXVzLmh0bWw.\">boosters<\/a>\u00a0for those who have already completed a primary series of Pfizer-BioNTech vaccination in those ages \u2265 65 years or at high risk of severe COVID-19 as well as those with occupational\/ institutional exposure risk, based on waning protection from infection after 6 months. The VDH has updated their\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=Iqd8sw_OdSQDSYG8dvGBQq3iGaKc2wk_uHJjDS5L0tjM-weJNYXZCAFodHRwczovL3d3dy52ZGgudmlyZ2luaWEuZ292L2NvdmlkLTE5LWZhcS92YWNjaW5hdGlvbi8jYm9vc3Rlcg..\">FAQs<\/a>\u00a0page, and vaccine providers, including at UVA, will begin scheduling boosters in October. Booster dose recommendations for Moderna and J&amp;J vaccines are expected to follow by mid-October, pending further review by the CDC and FDA.<\/p>\n<p><strong><em>COVID-19 vaccines and children<\/em><\/strong>. The Pfizer-BioNTech companies have submitted their initial data from their Phase 2\/3 clinical trial of the COVID-19 vaccine in children 5-11 years of age to the FDA. In\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=792kJMdeLOP8eiWG-rfLCX4kmM4vqxlDcE_1ZxezjXPM-weJNYXZCAFodHRwczovL3d3dy5wZml6ZXIuY29tL25ld3MvcHJlc3MtcmVsZWFzZS9wcmVzcy1yZWxlYXNlLWRldGFpbC9wZml6ZXItYW5kLWJpb250ZWNoLXN1Ym1pdC1pbml0aWFsLWRhdGEtdXMtZmRhLXBpdm90YWw.\">press release<\/a>, they report a two-dose regimen of 10 ug (the dose selected based on prior study) separated by 21 days achieved robust immune responses similar to the 16-25 year age group using immunobridging studies, with similar tolerability. This news provides promising hope that we may have a safe and effective vaccine for this age group soon. Results from the other two Pfizer age cohort studies (2-5 years and &lt; 2 years) are expected at the end of the year. In the meantime, everyone ages 2 years and up should wear a mask in public indoor spaces. Two new studies confirm that masks do indeed provide an additional layer of protection to children in school and daycare. In\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=fhMXDLxn1pbOP36_T1f4lfFaq59biAZpBeVVglphrUnM-weJNYXZCAFodHRwczovL3d3dy5jZGMuZ292L21td3Ivdm9sdW1lcy83MC93ci9tbTcwMzllMS5odG0_c19jaWQ9bW03MDM5ZTFfdw..\">Arizona<\/a>, where school started one month earlier than in Virginia, schools without mask mandates were 3.5 times as likely to have COVID-19 outbreaks than schools that started the year with mask requirements. Another\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=nue0E_RHt0cktEaW_7x6oE39sTiYW4xoWZx3ydA8lI3M-weJNYXZCAFodHRwczovL3d3dy5jZGMuZ292L21td3Ivdm9sdW1lcy83MC93ci9tbTcwMzllMy5odG0_c19jaWQ9bW03MDM5ZTNfdw..\">study<\/a>\u00a0looking at over 500 counties in the US found that pediatric cases increased at a higher rate in those without school mask mandates, providing good support for our own\u00a0<a href=\"https:\/\/email.healthsystem.virginia.edu\/owa\/redir.aspx?REF=-0eQJdRDNBWDDbxZxMsihdp3OCb7XbEqF6EN_ksOO_TM-weJNYXZCAFodHRwczovL3d3dy52ZGgudmlyZ2luaWEuZ292L2Nvcm9uYXZpcnVzL3Byb3RlY3QteW91cnNlbGYvbWFzay1yZXF1aXJlbWVudHMtYW5kLXJlY29tbWVuZGF0aW9uLw..\">state<\/a>\u00a0mask requirements in school.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>COVID-19 children\u2019s corner: brief updates on epidemiology, variants, vaccines and more\u2026 by Dr. Debbie-Ann Shirley, MD The pandemic and children.\u00a0Nearly\u00a05.8 million\u00a0child cases of COVID-19 have been reported in the United States to date, with at least 561 deaths. Nationally over 206,864 new child COVID-19 cases were reported\u00a0in the week ending September 23rd, with children accounting [&hellip;]<\/p>\n","protected":false},"author":338,"featured_media":2901,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[270],"class_list":["post-3130","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-features","tag-ds3ru"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>COVID-19 Children\u2019s Corner: October - Monthly Matters<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/news.med.virginia.edu\/kidsmatter\/covid-19-childrens-corner-october\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COVID-19 Children\u2019s Corner: October - Monthly Matters\" \/>\n<meta property=\"og:description\" content=\"COVID-19 children\u2019s corner: brief updates on epidemiology, variants, vaccines and more\u2026 by Dr. Debbie-Ann Shirley, MD The pandemic and children.\u00a0Nearly\u00a05.8 million\u00a0child cases of COVID-19 have been reported in the United States to date, with at least 561 deaths. 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