{"id":1216,"date":"2019-03-31T18:37:28","date_gmt":"2019-03-31T22:37:28","guid":{"rendered":"https:\/\/news.med.virginia.edu\/fac-dev-blog\/?p=1216"},"modified":"2020-02-21T15:42:00","modified_gmt":"2020-02-21T20:42:00","slug":"uva-som-faculty-news-weekly-round-up-march-29-2019","status":"publish","type":"post","link":"https:\/\/news.med.virginia.edu\/fac-dev-blog\/2019\/03\/31\/uva-som-faculty-news-weekly-round-up-march-29-2019\/","title":{"rendered":"UVA SOM Faculty News Weekly Round-Up: March 29, 2019"},"content":{"rendered":"<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"au41o-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"au41o-0-0\"><span data-offset-key=\"au41o-0-0\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1192 size-full\" src=\"https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News.jpg\" alt=\"Graphic showing Faculty News Weekly Round-Up at UVA School of Medicine.\" width=\"576\" height=\"576\" srcset=\"https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News.jpg 576w, https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News-150x150.jpg 150w, https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News-300x300.jpg 300w, https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News-200x200.jpg 200w, https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News-100x100.jpg 100w, https:\/\/news.med.virginia.edu\/fac-dev-blog\/files\/2019\/03\/Image-UVA-Faculty-News-70x70.jpg 70w\" sizes=\"(max-width: 576px) 100vw, 576px\" \/>UVA SOM Faculty News Weekly Round-Up<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"eph6-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"eph6-0-0\"><span data-offset-key=\"eph6-0-0\">March 29, 2019<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"igg-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"igg-0-0\"><span data-offset-key=\"igg-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"f597e-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"f597e-0-0\"><span data-offset-key=\"f597e-0-0\">\u2022 Testosterone Discovery May Explain Low Levels in Men with Diabetes<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"1ne38-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1ne38-0-0\"><span data-offset-key=\"1ne38-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"cqmp7-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"cqmp7-0-0\"><span data-offset-key=\"cqmp7-0-0\">Scientists have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"dr0he-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"dr0he-0-0\"><span data-offset-key=\"dr0he-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"6tgkn-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"6tgkn-0-0\"><span data-offset-key=\"6tgkn-0-0\">The discovery lets scientists understand exactly how testosterone, the male sex hormone, binds to a protein called serum albumin and can be carried through the body.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"6m5v8-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"6m5v8-0-0\"><span data-offset-key=\"6m5v8-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"4jq31-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"4jq31-0-0\"><span data-offset-key=\"4jq31-0-0\">The finding suggests that many drugs bind to serum albumin in the same way as testosterone, potentially explaining why the drugs interfere with normal testosterone transport. Further, the researchers report a similar overlap may explain why low testosterone is common in men with type 2 diabetes.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"4ogcp-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"4ogcp-0-0\"><span data-offset-key=\"4ogcp-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"9obj8-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"9obj8-0-0\"><span data-offset-key=\"9obj8-0-0\">\u201cThis represents a key finding from one of many albumin-related projects investigated in our laboratory. We study human and equine serum albumins but are interested in bovine, rat, mouse and rabbit serum albumins as well. These projects have been active for more than a decade in the lab,\u201d said principal investigator Wladek Minor, PhD, of the School of Medicine. \u201cBut we cannot stop our research here. We must address the next big challenge, which is the determination of albumin structures in complex with commonly used and abused opioids. We believe that the determination of these structures may be crucial in the development of new methods and treatments as our country combats the opioid crisis.\u201d<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"acaaa-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"acaaa-0-0\"><span data-offset-key=\"acaaa-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"dasos-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"dasos-0-0\"><span data-offset-key=\"dasos-0-0\">The researchers have published their findings in the journal Chemical Science. The article was featured as the journal\u2019s outside back cover story for the Feb. 14 issue. The research team consisted of Mateusz Czub, Barat Venkataramany, Karolina A. Majorek, Katarzyna B. Handing, Przemyslaw J. Porebski, Sandya R. Beeram, Kyungah Suh, Ashley G. Woolfork, Hage, Ivan G. Shabalin and Minor.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"39ldo-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"39ldo-0-0\"><span data-offset-key=\"39ldo-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"686u4-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"686u4-0-0\"><span data-offset-key=\"686u4-0-0\">Read more: https:\/\/newsroom.uvahealth.com\/2019\/03\/27\/testosterone-discovery-may-explain-low-levels-in-men-with-diabetes\/ <\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"b8p38-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"b8p38-0-0\"><span data-offset-key=\"b8p38-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"f8n56-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"f8n56-0-0\"><span data-offset-key=\"f8n56-0-0\">\u2022 UVA Honored on National List of Great Neurosurgery, Spine Programs<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"16omt-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"16omt-0-0\"><span data-offset-key=\"16omt-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"cavc2-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"cavc2-0-0\"><span data-offset-key=\"cavc2-0-0\">Becker&#8217;s Hospital Review has named the University of Virginia Medical Center as one of 100 hospitals and health care systems with great neurosurgery and spine programs, marking the fifth consecutive year it has earned this honor.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"3iphq-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"3iphq-0-0\"><span data-offset-key=\"3iphq-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"1h92r-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1h92r-0-0\"><span data-offset-key=\"1h92r-0-0\">Becker&#8217;s highlighted UVA&#8217;s efforts over the past two decades to provide innovative spine and neurosurgery care, citing UVA&#8217;s work with Gamma Knife radiosurgery and focused ultrasound.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"bus29-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"bus29-0-0\"><span data-offset-key=\"bus29-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"5hhhb-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"5hhhb-0-0\"><span data-offset-key=\"5hhhb-0-0\">&#8220;Our clinicians and researchers are constantly seeking new and better ways to care for our patients, and I am proud to see those efforts recognized by Becker&#8217;s Hospital Review,&#8221; said Dr. Mark Shaffrey, chair of UVA&#8217;s Department of Neurosurgery.<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"c6u29-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"c6u29-0-0\"><span data-offset-key=\"c6u29-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"7umjg-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"7umjg-0-0\"><span data-offset-key=\"7umjg-0-0\">Read more: https:\/\/news.virginia.edu\/content\/accolades-uva-honored-national-list-great-neurosurgery-spine-programs<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"e4dj1-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"e4dj1-0-0\"><span data-offset-key=\"e4dj1-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"drpbh-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"drpbh-0-0\"><span data-offset-key=\"drpbh-0-0\">\u2022 Faculty Recognitions<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"1lov9-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1lov9-0-0\"><span data-offset-key=\"1lov9-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"1drer-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1drer-0-0\"><span data-offset-key=\"1drer-0-0\">&#8211; Alan Matsumoto, MD, was honored with a SIR Gold Medal at the 2019 Society of Interventional Radiology Annual Meeting in Austin. Dr. Matsumoto also gave the Dotter Lecture at the conference, where he said, \u201cDoing what\u2019s best for our patients should always be our true north and guiding compass.\u201d<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"le16-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"le16-0-0\"><span data-offset-key=\"le16-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"6ipcm-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"6ipcm-0-0\"><span data-offset-key=\"6ipcm-0-0\">&#8211; Silvia Blemker, PhD, has been inducted as a Fellow of the American Institute for Medical and Biological Engineering<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"7vifd-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"7vifd-0-0\"><span data-offset-key=\"7vifd-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"bvk7i-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"bvk7i-0-0\"><span data-offset-key=\"bvk7i-0-0\">&#8212;<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"t0v3\" data-offset-key=\"1l1fg-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1l1fg-0-0\"><span data-offset-key=\"1l1fg-0-0\">Did we miss something? If you have UVA SOM faculty news to share, please email christa@virginia.edu. <\/span><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>UVA SOM Faculty News Weekly Round-Up March 29, 2019 \u00a0 \u2022 Testosterone Discovery May Explain Low Levels in Men with Diabetes \u00a0 Scientists have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications. \u00a0 The discovery lets scientists [&hellip;]<\/p>\n","protected":false},"author":216,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-1216","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>UVA SOM Faculty News Weekly Round-Up: March 29, 2019 - 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