Medical Technology Enterprise Consortium (MTEC) – upcoming opportunity on Prototype Acceleration

MTEC has posted a pre-announcement for a Request for Project Proposal for Prototype Acceleration efforts that will focus on advancing novel prototype technologies into the next major stage of development/milestone dependent upon their current maturity.  Examples of the next major stage of development/milestone include, but are not limited to:  late animal testing and regulatory filing, manufacturing, next clinical trial, regulatory approval, etc.

To be eligible, prototypes must fulfill a recognized research need/capability gap that will be described in the Request for Project Proposals and must be (at a minimum) Technology Readiness Level 4*.  Proposals must have an overarching objective that demonstrates significant advancement in the readiness of the technology within a 12 month period of performance.  Overall costs for an award may range from $150,000 – $300,000.  Proposed efforts must be based on logical reasoning and sound scientific rationale.  Please note that MTEC projects must eventually result in prototype deliverables that transition medical solutions to dual-use markets.

The Prototype Acceleration Award mechanism is not intended to support basic research or research involving human subjects.  Preliminary data are required. 

Planned focus areas for the Prototype Acceleration Award solicitation include:

Wound Care/Anti-infectives to include point of injury wound care

  • Novel platforms for the delivery of wound care anti-infectives
  • Novel anti-infectives with the ability to prevent the development of infections post injury
  • Novel anti-infectives that reduce inflammation and pain sensation
  • Therapies to fight antimicrobial resistance
  • Novel treatments for skin/wound infection

Regenerative Medicine

  • Biologic therapies for muscle regeneration
  • Novel platforms for regenerative medicine applications to include bone regeneration, bone grafting, and rebuilding tissues or skin after injury (e.g., burn injury)

All Offerors responding to this prototype acceleration opportunity are required to be members of MTEC. The Prototype Acceleration opportunity will be posted to the MTEC website, in addition there will be a FedBiz Opps posting to notify interested parties.  For more information about joining MTEC, please visit

*  Technical Readiness Level 4 (per Department of Defense):

  • Component and/or breadboard validation in laboratory environment.
  • Basic technological components are integrated to establish that they will work together. This is relatively “low fidelity” compared with the eventual system. Examples include integration of “ad hoc” hardware in the laboratory.
  • System concepts that have been considered and results from testing laboratory-scale breadboard(s). References to who did this work and when. Provide an estimate of how breadboard hardware and test results differ from the expected system goals.