NIH – Centers of Research Translation (CORT) (P50 Clinical Trial Not Allowed)

December 11, 2020 by


This Funding Opportunity Announcement (FOA) invites applications for Centers of Research Translation (CORT). Overall, a CORT research program should be carried out by a synergistic team of scientists who, through an interdisciplinary team science approach, will address a highly significant translational research challenge in a single or a group of highly-related disease(s) or condition(s) within the mission of the NIAMS. The focus of research could be either 1) a disease-targeted translational theme addressed by synergistic Research Projects with optional Research Cores; or 2) a disease-related critical translational research question addressed through a single collaborative Research Project enabled by a number of highly interactive Research Cores whose work is integrated during the development and implementation of the Project. A CORT must have a minimum of three highly meritorious research components consisting of one or more translational Research Projects and optional Research Cores. An Administrative Core is required in all applications. To facilitate an interdisciplinary team science approach, the lead investigators of the research components must be drawn from relevant and, as appropriate, different research disciplines, and may be based in different departments, divisions, and/or institutions. Combined, the projects and cores will generate new knowledge that will improve our understanding of human pathophysiology and lead to identification of new targets, other tangible products or deliverables, and development of more effective treatment, diagnostic, or prevention strategies for human disease.


A CORT must focus on a single or a group of highly-related disease(s) entities or disorders in the NIAMS mission, although the proposed research may be relevant to more than one disease and an additional disease(s) may be used as a control if scientifically justified. The focus cannot be generic, e.g., autoimmune diseases, rheumatic and musculoskeletal disorders, or skin diseases. Potential PDs/PIs are strongly encouraged to contact the Scientific/Research Contacts for this FOA early in the application planning process to discuss NIAMS mission relevance.

Key Dates:

Letter of Intent Due Date(s): 30 days prior to the application due date

Application Due Date(s): May 11, 2021

URL for more information:

Filed Under: Funding Opportunities