This Funding Opportunity Announcement (FOA) invites applications for centers to support transdisciplinary teams of clinical and mental health services researchers, behavioral scientists, social scientists, health information and communications technologists, health systems engineers, decision scientists, and mental health stakeholders (e.g., service users, family members, clinicians, payers) to engage in high-impact studies that will significantly advance clinical practice and generate knowledge that will fuel transformation of mental health care in the United States. Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers will support the rapid development, testing, and refinement of novel and integrative approaches for (1) optimizing the effectiveness of therapeutic or preventive interventions for mental disorders within well-defined target populations; (2) organizing and delivering optimized mental health services within real world treatment settings; and (3) continuously improving the quality, impact, and durability of optimized interventions and service delivery within diverse care systems. The ALACRITY Centers program is intended to support research that maximizes synergies across various components of the mental health research ecosystem, including new discoveries in clinical research, transformative health care technologies, advances in information science, and new federal and state mechanisms for organizing mental health care. The Centers are intended for transdisciplinary projects that could not be achieved using standard research project grant mechanisms. The ALACRITY Centers program is also expected to facilitate widespread sharing of relevant data, methods, and resources that will accelerate clinical research and practice and to provide opportunities for graduate students, postdoctoral researchers, and early-career investigators to participate in transdisciplinary, T2 translational mental health research.
Applicants interested in submitting applications to support transdisciplinary programs of research focused on identification, prevention, and treatment of suicide risk, specifically, are directed to PAR-20-286 (“Practice-Based Suicide Prevention Research Centers (P50)”).
In any given year, nearly one-fifth of all U.S. adults struggle with a mental illness. According to recent estimates, mental illnesses account for 21.3 percent of all years lived with disability in the United States. An estimated 11.4 million American adults suffer from a serious mental illness (SMI) in which the ability to function in daily life is significantly impaired. Those with SMI die 10 years earlier than individuals in the general population, on average. A conservative estimate places the direct and indirect financial costs associated with mental illnesses in the United States at well over $300 billion annually. Mental illnesses rank as the third most costly medical conditions in terms of overall health care expenditure, behind heart conditions and traumatic injury. In addition, between two and four hundred thousand men and women with SMI are incarcerated in U.S. jails and prisons, where they may receive inadequate treatment and often no aftercare following release to the community. This public health burden demands that we combine current knowledge about effective mental disorder treatments with emerging health information and communication technologies, health care informatics, data science tools, and novel organizational structures for delivering health care to achieve significantly better outcomes for these disabling conditions.
Furthermore, in 2019, more than 47,000 Americans died from suicide, more than twice the annual mortality from homicide. Suicide attempts and ideation far exceed these numbers. (Applicants interested in submitting applications to support transdisciplinary programs of research focused on identification, prevention, and treatment of suicide risk, specifically, are directed to PAR-20-286 (“Practice-Based Suicide Prevention Research Centers (P50)”)).
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Filed Under: Funding Opportunities