Medical Technology Enterprise Consortium (MTEC) – Prototype Development

March 10, 2020 by dld5dt@virginia.edu

Purpose:

The MOMRP has identified two focus areas for funding under this RPP. To meet the intent of this RPP, each proposal MUST specifically address only ONE of the two Focus Areas described below. Offerers are not limited to a single proposal submission. Projects not aligned to at least one of these Focus Areas will not be considered for funding. It is expected that MTEC will make a total of 2 awards – a single award for each focus area…

1)      FOCUS AREA #1 (Whole Body Blast): Development of survivability criteria and vital organ injury metrics for the whole body when exposed to extreme blast exposures.

Background:

Personal protection equipment (PPE) for the Warfighter has been designed to primarily protect against injuries from projectiles, shrapnel, debris and blunt object impact in training and combat operational environments. At present, there are no appropriate guidelines and test methodologies to evaluate the protective performance of PPE, such as body armor and bomb suits, against primary blast. Therefore, this project aims to develop survivability criteria and vital organ injury metrics relevant to personnel exposed to potentially lethal primary blast, such as that resulting from improvised explosive devices (IEDs).

SCOPE OF WORK:

During the PoP, the Awardee shall establish medically-based criteria (i.e., blast injury risk curves) for evaluation of the protective efficacy of PPE (i.e., bomb suits and body armor) for Warfighters.

The Awardee shall address the following tasks:

  • Establish metrics to assess the effectiveness of PPE against primary blast using biological surrogate models.
  • Develop survivability dose-response relationships and vital organ blast injury criteria for primary blast exposure.
  • Utilize different animal experimental models (i.e., differently scaled species) in conjunction with surrogate models to define blast-induced injuries and scaling factors for blast-induced vital organ injury (e.g., brain and lung) that can be readily translated to humans.
  • Define biomechanical parameters associated with established injury levels for individual vital organs and cognitive functional outcomes.

The Awardee will be expected to coordinate with research leads (i.e., subject matter experts) at the Walter Reed Army Institute of Research (WRAIR) and DoD investment stakeholders in relation to this project. At the time of award, the Government will provide the Awardee with a point of contact at WRAIR to enable direct interactions.

2)      FOCUS AREA #2 (Cognitive/Brain Health & Performance): Validation of personalized training and/or materiel (pharmacological/technological) approaches to build and enhance cognitive/brain health, performance and psychological health.

BACKGROUND:

Multi-domain operations will involve significant demands on Warfighter cognitive agility and resistance to a multitude of stressors. There is a lack of rigorously tested cognitive training and enhancing tools and a dearth of data demonstrating effectiveness of such tools on operationally relevant tasks, psychological health outcomes, and brain health. There is also a lack of prospective longitudinal data to understand appropriate training protocols and requirements (e.g., training dosing, duration).

SCOPE OF WORK:

During the PoP, the Awardee shall:

  • Develop or adapt cognition-promoting training or materiel solutions suitable for military application and training pipelines (e.g., feasible, scalable, efficient, low-cost).
  • Demonstrate efficacy of training or materiel to positively impact cognitive performance (as measured by operationally relevant tasks including, but not limited to, perception, attention and memory) and psychological health outcomes in healthy as well as injured Warfighters.
  • Elucidate active components of the cognitive training or materiel and relative contribution to outcomes in order to streamline and optimize military-relevant training.

END GOAL: Deliver an efficient and effective method for personalized training to build and enhance cognitive/brain health, performance and psychological health.

POTENTIAL FUNDING:

The U.S. Department of Defense (DoD) currently has available approximately $5.14 million (M) of Fiscal Year (FY) 2019 Defense Health Program (DHP) funds for anticipated awards. The estimated total funding available per Focus Area is as follows:

1)      FOCUS AREA #1 (Whole Body Blast): $2.78 Million

2)      FOCUS AREA #2 (Cognitive / Brain Health & Performance): $2.36 Million

Any potential follow-on funding would be negotiated based on outcomes, cost sharing, partner matching and estimates for additional study completion.

It is expected that MTEC will make a total of 2 awards (a single award for each focus area) to qualified teams to accomplish the statement of work. If a single proposal is unable to sufficiently address the entire scope of a specific focus area, several Offerors may be asked to work together in a collaborative manner. However, if an optimal team is not identified, then MTEC may make multiple, individual awards to Offeror(s) to accomplish subset(s) of the key tasks.

The Period of Performance (POP) is not to exceed three years.

Key Dates:

Full proposals are due no later than April 8, 2020 at 12:00pm Eastern Time. The RPP will be posted to the MTEC website (mtec-sc.org) and a notice will be posted on www.beta.SAM.gov to notify interested parties. MTEC membership is required for the submission of a full proposal in response to this MTEC RPP. Offerors submitting Full Proposals as the prime contractor must be MTEC members of good standing by April 3, 2020.  To join MTEC, please visit http://mtec-sc.org/how-to-join/

POINTS OF CONTACT:

Please direct your inquiries and correspondence to the following contacts:

To view this solicitation, click here.

Filed Under: Funding Opportunities