NIH – Research on biopsychosocial factors of social connectedness and isolation on health, wellbeing, illness, and recovery (R01 Clinical Trials Not Allowed)

September 20, 2019 by


This funding opportunity announcement (FOA) solicits research projects that seek to model the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in health, illness, recovery, and overall wellbeing.


It is well-established that social ties can facilitate overall wellbeing, recovery from acute illness, and self-management of chronic conditions. Less well understood are the processes by which connection and isolation lead to positive or negative impacts on health, wellbeing, illness, or recovery. A more comprehensive understanding of the mechanisms, processes, and trajectories involved in social connectedness and isolation may identify novel targets to inform future intervention developments and to strengthen individual and group functions.

This FOA solicits research to better model the basic individual, social, and biobehavioral processes by which social connectedness and isolation have positive or negative impacts across the lifespan. It encourages projects that accelerate our understanding among relationships between various factors, including those that can be objectively measured (e.g., biomeasures, health records data, occurrence or length of relationship disruption) and those that require self-report and/or can be objectively observed and reported.

Key Dates

Open Date (Earliest Submission Date): February 17, 2020
Letter of Intent Due Date(s): Not applicable.
Application Due Date(s): March 17, 2020; March 17, 2021,

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Filed Under: Funding Opportunities