NIH – Research Networks for the Study of Recovery Support Services for Persons Treated with Medications for Opioid Use Disorder (R24 Clinical Trial Optional)

September 20, 2019 by


This FOA invites applications to provide infrastructure support for advancing the development of high-priority effectiveness research on recovery support services for individuals with opioid use disorder who received or who are being maintained on an FDA-approved medication for the treatment of this disorder. The infrastructure support will facilitate multi-stakeholder research networks through meetings, conferences, small-scale pilots, data development activities, short-term educational opportunities (such as intensive workshops, summer institutes, or visiting scholar programs), and dissemination to encourage growth and development of specified priority areas and build resources for advancing recovery support services efficacy/effectiveness research in the field at large. NIDA defines recovery as a process of change through which people improve their health and wellness, live self-directed lives, and strive to reach their full potential, and being in recovery is when positive changes and values become part of a voluntarily adopted lifestyle. Other definitions of recovery may exist and be relevant to this RFA. Recovery support services are thought to assist individuals with the recovery process.


Effective treatments for opioid use disorders exist but may not be sufficient to assure long-term reductions in use and return to functioning. Though patients may be stabilized via formal treatment, changes in the structure and functioning of the brain due to drug use may affect reward processes, memory, motivation, impulse control and judgement that may take months or years to resolve and leave individuals vulnerable to resumption of use. At the same time, addictive behaviors may lead to unemployment, housing loss, criminal justice system involvement, and social isolation that can hamper a return to functioning. Furthermore, recovery needs may differ across the lifespan. Recovery support services have been developed to provide a variety of non-clinical services such as recovery coaching, linkages to employment, training and other social services, opportunities for rewarding social community activities, and community engagement, to address these needs. Such services may be provided as part of peer-based recovery supports, or by peers or professionals in recovery community centers, active recovery communities, recovery residences, and/or recovery high schools/collegiate recovery programs. Clinical continuing care services provided by professionals have also been designed to assist individuals during recovery. Although such services are proliferating, their effectiveness has not been adequately studied, and they may not be designed to meet the needs of individuals who have been prescribed medications approved by the FDA for the treatment of opioid use disorder, especially those who wish to continue on these medications indefinitely.

Key Dates

Open Date (Earliest Submission Date): October 19, 2019
Letter of Intent Due Date(s): October 19, 2019
Application Due Date(s): November 19, 2019 by 5:00 PM local time of applicant organization.
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Filed Under: Funding Opportunities