Purpose
The purpose of these Funding Opportunity Announcements (FOAs) is to solicit applications from investigators to participate in the HLA and KIR Region Genomics in Immune Mediated Diseases Consortium (HLARGC). These cooperative research groups will support projects defining the association between variations in the human leukocyte antigen (HLA), also known as the Major Histocompatibility Complex (MHC), and natural killer cell immunoglobulin-like receptor (KIR) genetic regions and immune-mediated diseases, including outcomes following cell, tissue, and organ transplantation.
In addition to supporting HLA and KIR region association studies, a major goal of this program is the assemblage of high-quality, high-resolution genetic data with accompanying disease state and phenotype information. The data generated by the HLARGC will be submitted to the NIAID Bioinformatics Information Support Contract database, the Immunology Database and Analysis Portal (ImmPort). Where appropriate, data from these studies will also be submitted to Database of Genotypes and Phenotypes (dbGaP) and other publicly accessible databases.
Mechanisms
U01 Research Project – Cooperative Agreements
U19 Research Program – Cooperative Agreements
Posted Date – May 2, 2019
Filed Under: Funding Opportunities